Role of Genes in the Pathogenesis of Pancreatitis and Pancreatic Cancer

Author Details

Feng Gao, Hui-liang Zhou, Yunfeng Lin, Feng Dong, Yu-jia Guo, Qicai Liu

Journal Details

Journal of Genetics and Genetic Engineering - ISSN - 2637-5370, Volume 3, Issue 1

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Published: 7 February 2019 | Article Type :

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doi 10.22259/2637-5370.0301003

Abstract

The metastatic progression of pancreatic cancer is greatly attributed to the intercellular communication. It has found serine protease 1 (PRSS1) mutations associated with pancreatic cancer and hereditary pancreatitis. In the long-time “injury-inflammation-cancer” pathway has more and more evidences to support. This review describes the factors closely related to hereditary pancreatitis from the genetic level and how to develop from pancreatitis to pancreatic cancer.

Keywords: pancreatitis; pancreatic cancer; PRSS1; SPINK1; CFTR, CTRC; K-Ras.

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Volume 3, Issue 1

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Citation:

Feng Gao, Hui-liang Zhou, Yunfeng Lin, Feng Dong, Yu-jia Guo, Qicai Liu. (2019-02-07). "Role of Genes in the Pathogenesis of Pancreatitis and Pancreatic Cancer." *Volume 3*, 1, 11-14